The DEP operates 53 foreign trade promotion offices in 38 target countries to foster market expansion and build Thailand's brand image to be widely recognized and accepted worldwide. The offices also serve in arranging business negotiations between exporters and buyers, and in coordinating with the public and private sectors to form trade missions and organize exhibitions, trade fairs and other marketing activities such as in-store promotions.

Another prime mission for the network is to continually update information concerning economy and trade, for example market movements, sales strategies, distribution channels, product development, competition, and changes in regulations that could affect Thailand's exports.

Other important roles of the Office of Foreign Trade Promotion include exploring more efficient sources of raw materials, advising on developments to reduce manufacturing costs, and helping to find new overseas business partners for Thai producers.